NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

A0A0S4TER9 — Bifunctional dihydrofolate reductase-thymidylate synthase

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB02338

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DB02338

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
A0A0S4TER9	DB02338	6ojs	NDP	A	601	e6ojsA2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6ojs	NDP	B	601	e6ojsB2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6ojs	NDP	C	601	e6ojsC2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6ojs	NDP	D	601	e6ojsD1	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6ojs	NDP	E	601	e6ojsE2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pf7	NDP	A	601	e6pf7A2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pf7	NDP	B	601	e6pf7B1	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pf7	NDP	C	601	e6pf7C1	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pf7	NDP	D	601	e6pf7D2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pf7	NDP	E	601	e6pf7E2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pf8	NDP	A	601	e6pf8A2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pf8	NDP	B	601	e6pf8B1	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pf8	NDP	C	601	e6pf8C2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pf8	NDP	D	601	e6pf8D2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pf8	NDP	E	601	e6pf8E2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pf9	NDP	A	601	e6pf9A2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pf9	NDP	B	601	e6pf9B2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pf9	NDP	C	601	e6pf9C2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pf9	NDP	D	601	e6pf9D1	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pf9	NDP	E	601	e6pf9C1	Thymidylate synthase/dCMP hydroxymethylase	Thymidylate synthase/dCMP hydroxymethylase	Thymidylate synthase/dCMP hydroxymethylase	Thymidylat_synt
A0A0S4TER9	DB02338	6pf9	NDP	E	601	e6pf9E2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfa	NDP	A	601	e6pfaA1	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfa	NDP	B	601	e6pfaB2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfa	NDP	C	601	e6pfaC1	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfa	NDP	D	601	e6pfaD2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfa	NDP	E	601	e6pfaE1	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfb	NDP	A	601	e6pfbA2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfb	NDP	B	601	e6pfbB2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfb	NDP	C	601	e6pfbC1	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfb	NDP	D	601	e6pfbD1	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfb	NDP	E	601	e6pfbE2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfc	NDP	A	601	e6pfcA1	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfc	NDP	B	601	e6pfcB1	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfc	NDP	C	601	e6pfcC1	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfc	NDP	C	601	e6pfcD1	Thymidylate synthase/dCMP hydroxymethylase	Thymidylate synthase/dCMP hydroxymethylase	Thymidylate synthase/dCMP hydroxymethylase	Thymidylat_synt
A0A0S4TER9	DB02338	6pfc	NDP	D	601	e6pfcD2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfc	NDP	E	601	e6pfcE2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfd	NDP	A	601	e6pfdA1	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfd	NDP	B	601	e6pfdB1	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfd	NDP	C	601	e6pfdC2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfd	NDP	D	601	e6pfdD1	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfd	NDP	E	601	e6pfdE2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfe	NDP	A	601	e6pfeA1	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfe	NDP	B	601	e6pfeB2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfe	NDP	C	601	e6pfeC1	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfe	NDP	D	601	e6pfeD2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfe	NDP	E	601	e6pfeE1	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pff	NDP	A	601	e6pffA2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pff	NDP	B	601	e6pffB1	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pff	NDP	C	601	e6pffC2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pff	NDP	D	601	e6pffD1	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pff	NDP	E	601	e6pffE1	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfg	NDP	A	601	e6pfgA1	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfg	NDP	B	601	e6pfgB1	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfg	NDP	C	601	e6pfgB2	Thymidylate synthase/dCMP hydroxymethylase	Thymidylate synthase/dCMP hydroxymethylase	Thymidylate synthase/dCMP hydroxymethylase	Thymidylat_synt
A0A0S4TER9	DB02338	6pfg	NDP	C	601	e6pfgC2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfg	NDP	D	601	e6pfgD2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfg	NDP	E	601	e6pfgE2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfh	NDP	A	601	e6pfhA1	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfh	NDP	B	601	e6pfhB1	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfh	NDP	B	601	e6pfhD1	Thymidylate synthase/dCMP hydroxymethylase	Thymidylate synthase/dCMP hydroxymethylase	Thymidylate synthase/dCMP hydroxymethylase	Thymidylat_synt
A0A0S4TER9	DB02338	6pfh	NDP	C	601	e6pfhC2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfh	NDP	D	601	e6pfhD2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfh	NDP	E	601	e6pfhE2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfi	NDP	A	601	e6pfiA2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfi	NDP	B	601	e6pfiB2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfi	NDP	C	601	e6pfiC1	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfi	NDP	D	601	e6pfiD1	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6pfi	NDP	E	601	e6pfiE1	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6wep	NDP	A	601	e6wepA2	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1
A0A0S4TER9	DB02338	6wep	NDP	B	601	e6wepB1	Dihydrofolate reductases	Dihydrofolate reductases	Dihydrofolate reductases	DHFR_1