Attributes
UniProt ID
Protein Name
Bifunctional dihydrofolate reductase-thymidylate synthase
Ligand Name
2-({4-[(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]benzene-1-carbonyl}amino)benzoic acid
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
NQGAZNWSUPTLIO-UHFFFAOYSA-N
SMILES
c1ccc(c(c1)C(=O)O)NC(=O)c2ccc(cc2)Cc3c[nH]c4c3C(=O)N=C(N4)N
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 6PF7
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Color Legend
Unassigned regionsLigand / hetero atomse6pf7A1e6pf7A2e6pf7B1e6pf7B2e6pf7C1e6pf7C2e6pf7D1e6pf7D2e6pf7E1e6pf7E2
ECOD domains from experimental PDB structures interacting with ligand OG7
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| A0A0S4TER9 | n/a | OG7 | 6pf7 | e6pf7A1 | A:182-521 |
| A0A0S4TER9 | n/a | OG7 | 6pf7 | e6pf7B2 | B:180-521 |
| A0A0S4TER9 | n/a | OG7 | 6pf7 | e6pf7C2 | C:180-521 |
| A0A0S4TER9 | n/a | OG7 | 6pf7 | e6pf7D1 | D:180-521 |
| A0A0S4TER9 | n/a | OG7 | 6pf7 | e6pf7E1 | E:180-521 |