Attributes
UniProt ID
Protein Name
Serine hydroxymethyltransferase
Ligand Name
(4R)-6-azanyl-4-[3-(hydroxymethyl)-5-phenyl-phenyl]-3-methyl-4-propan-2-yl-1H-pyrano[2,3-c]pyrazole-5-carbonitrile
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
VVVOFJZXKJKHTD-DEOSSOPVSA-N
SMILES
Cc1c2c([nH]n1)OC(=C(C2(c3cc(cc(c3)c4ccccc4)CO)C(C)C)C#N)N
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 7V3D
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Color Legend
Unassigned regionsLigand / hetero atomse7v3dA1e7v3dA2e7v3dB1e7v3dB2
ECOD domains from experimental PDB structures interacting with ligand 5M5
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| A0A133CK16 | n/a | 5M5 | 7v3d | e7v3dA1 | A:277-411 |
| A0A133CK16 | n/a | 5M5 | 7v3d | e7v3dA2 | A:3-276 |
| A0A133CK16 | n/a | 5M5 | 7v3d | e7v3dB1 | B:277-412 |
| A0A133CK16 | n/a | 5M5 | 7v3d | e7v3dB2 | B:2-276 |
| A0A133CK16 | n/a | 5M5 | 7x5n | e7x5nA1 | A:277-411 |
| A0A133CK16 | n/a | 5M5 | 7x5n | e7x5nA2 | A:3-276 |
| A0A133CK16 | n/a | 5M5 | 7x5n | e7x5nB1 | B:2-276 |
| A0A133CK16 | n/a | 5M5 | 7x5n | e7x5nB2 | B:277-412 |