Attributes
UniProt ID
Protein Name
glycine hydroxymethyltransferase
Ligand Name
(4~{S})-6-azanyl-3-methyl-4-[3-(2-methylphenyl)-5-(trifluoromethyl)phenyl]-4-propan-2-yl-2~{H}-pyrano[2,3-c]pyrazole-5-carbonitrile
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
UBSNISIBQUMDAM-DEOSSOPVSA-N
SMILES
Cc1ccccc1c2cc(cc(c2)C(F)(F)F)C3(c4c([nH]nc4OC(=C3C#N)N)C)C(C)C
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 5XMU
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Color Legend
Unassigned regionsLigand / hetero atomse5xmuA2e5xmuA3e5xmuB2e5xmuB3e5xmuC2e5xmuC3
ECOD domains from experimental PDB structures interacting with ligand 8A0
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| A0A1G4H5I1 | n/a | 8A0 | 5xmu | e5xmuA2 | A:289-442 |
| A0A1G4H5I1 | n/a | 8A0 | 5xmu | e5xmuA3 | A:1-290 |
| A0A1G4H5I1 | n/a | 8A0 | 5xmu | e5xmuB2 | B:289-442 |
| A0A1G4H5I1 | n/a | 8A0 | 5xmu | e5xmuB3 | B:1-290 |
| A0A1G4H5I1 | n/a | 8A0 | 5xmu | e5xmuC2 | C:289-442 |
| A0A1G4H5I1 | n/a | 8A0 | 5xmu | e5xmuC3 | C:1-290 |