Attributes
UniProt ID
Protein Name
glycine hydroxymethyltransferase
Ligand Name
(4~{S})-6-azanyl-4-[3-(2-fluorophenyl)-5-(trifluoromethyl)phenyl]-3-methyl-4-propan-2-yl-2~{H}-pyrano[2,3-c]pyrazole-5- carbonitrile
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
ODGVACPFBGBPRF-QHCPKHFHSA-N
SMILES
Cc1c2c(n[nH]1)OC(=C(C2(c3cc(cc(c3)C(F)(F)F)c4ccccc4F)C(C)C)C#N)N
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 5XMS
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Color Legend
Unassigned regionsLigand / hetero atomse5xmsA2e5xmsA3e5xmsB2e5xmsB3e5xmsC2e5xmsC3
ECOD domains from experimental PDB structures interacting with ligand 8B3
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| A0A1G4H5I1 | n/a | 8B3 | 5xms | e5xmsA2 | A:289-442 |
| A0A1G4H5I1 | n/a | 8B3 | 5xms | e5xmsA3 | A:1-290 |
| A0A1G4H5I1 | n/a | 8B3 | 5xms | e5xmsB2 | B:289-442 |
| A0A1G4H5I1 | n/a | 8B3 | 5xms | e5xmsB3 | B:1-290 |
| A0A1G4H5I1 | n/a | 8B3 | 5xms | e5xmsC2 | C:289-442 |
| A0A1G4H5I1 | n/a | 8B3 | 5xms | e5xmsC3 | C:1-290 |