Attributes
UniProt ID
Protein Name
glycine hydroxymethyltransferase
Ligand Name
2-[1-[(3~{S})-6'-azanyl-5'-cyano-7-fluoranyl-2,2,3'-trimethyl-spiro[1~{H}-indene-3,4'-2~{H}-pyrano[2,3-c]pyrazole]-5-yl]piperidin-4-yl]ethanoic acid
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
IJNFEDVSEBDSHQ-RUZDIDTESA-N
SMILES
Cc1c2c(n[nH]1)OC(=C(C23c4cc(cc(c4CC3(C)C)F)N5CCC(CC5)CC(=O)O)C#N)N
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 5YG4
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Color Legend
Unassigned regionsLigand / hetero atomse5yg4A1e5yg4A2e5yg4B1e5yg4B2e5yg4C1e5yg4C2
ECOD domains from experimental PDB structures interacting with ligand 8UF
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| A0A1G4H5I1 | n/a | 8UF | 5yg4 | e5yg4A1 | A:291-442 |
| A0A1G4H5I1 | n/a | 8UF | 5yg4 | e5yg4A2 | A:1-290 |
| A0A1G4H5I1 | n/a | 8UF | 5yg4 | e5yg4B1 | B:1-290 |
| A0A1G4H5I1 | n/a | 8UF | 5yg4 | e5yg4B2 | B:291-442 |
| A0A1G4H5I1 | n/a | 8UF | 5yg4 | e5yg4C1 | C:1-290 |
| A0A1G4H5I1 | n/a | 8UF | 5yg4 | e5yg4C2 | C:291-442 |