Attributes
UniProt ID
Protein Name
glycine hydroxymethyltransferase
Ligand Name
3-[1-[3-[(4~{S})-6-azanyl-5-cyano-3-methyl-4-propan-2-yl-2~{H}-pyrano[2,3-c]pyrazol-4-yl]-5-(trifluoromethyl)phenyl]piperidin-4-yl]propanoic acid
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
FJQQQYACRNHDIU-VWLOTQADSA-N
SMILES
Cc1c2c(n[nH]1)OC(=C(C2(c3cc(cc(c3)N4CCC(CC4)CCC(=O)O)C(F)(F)F)C(C)C)C#N)N
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 5YG1
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Color Legend
Unassigned regionsLigand / hetero atomse5yg1A1e5yg1A2e5yg1B1e5yg1B2e5yg1C1e5yg1C2
ECOD domains from experimental PDB structures interacting with ligand 8UU
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| A0A1G4H5I1 | n/a | 8UU | 5yg1 | e5yg1A1 | A:1-290 |
| A0A1G4H5I1 | n/a | 8UU | 5yg1 | e5yg1A2 | A:291-442 |
| A0A1G4H5I1 | n/a | 8UU | 5yg1 | e5yg1B1 | B:291-442 |
| A0A1G4H5I1 | n/a | 8UU | 5yg1 | e5yg1B2 | B:1-290 |
| A0A1G4H5I1 | n/a | 8UU | 5yg1 | e5yg1C1 | C:1-290 |
| A0A1G4H5I1 | n/a | 8UU | 5yg1 | e5yg1C2 | C:291-442 |