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2-{3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-4-METHYL-2-OXO-2,3-DIHYDRO-1,3-THIAZOL-5-YL}ETHYL TRIHYDROGEN DIPHOSPHATE

A0A1H8YFL8 — 2-hydroxyacyl-CoA lyase 1

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand TZD

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand TZD

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
A0A1H8YFL8n/a6xn8TZDA602e6xn8A1Thiamin diphosphate-binding fold (THDP-binding)Thiamin diphosphate-binding fold (THDP-binding)Thiamin diphosphate-binding fold (THDP-binding)TPP_enzyme_C
A0A1H8YFL8n/a6xn8TZDA602e6xn8A3Thiamin diphosphate-binding fold (THDP-binding)Thiamin diphosphate-binding fold (THDP-binding)Thiamin diphosphate-binding fold (THDP-binding)TPP_enzyme_N
A0A1H8YFL8n/a6xn8TZDA602e6xn8B1Thiamin diphosphate-binding fold (THDP-binding)Thiamin diphosphate-binding fold (THDP-binding)Thiamin diphosphate-binding fold (THDP-binding)TPP_enzyme_N
A0A1H8YFL8n/a6xn8TZDB602e6xn8A1Thiamin diphosphate-binding fold (THDP-binding)Thiamin diphosphate-binding fold (THDP-binding)Thiamin diphosphate-binding fold (THDP-binding)TPP_enzyme_C
A0A1H8YFL8n/a6xn8TZDB602e6xn8A3Thiamin diphosphate-binding fold (THDP-binding)Thiamin diphosphate-binding fold (THDP-binding)Thiamin diphosphate-binding fold (THDP-binding)TPP_enzyme_N
A0A1H8YFL8n/a6xn8TZDB602e6xn8B1Thiamin diphosphate-binding fold (THDP-binding)Thiamin diphosphate-binding fold (THDP-binding)Thiamin diphosphate-binding fold (THDP-binding)TPP_enzyme_N
A0A1H8YFL8n/a6xn8TZDB602e6xn8B2Thiamin diphosphate-binding fold (THDP-binding)Thiamin diphosphate-binding fold (THDP-binding)Thiamin diphosphate-binding fold (THDP-binding)TPP_enzyme_C