Attributes
UniProt ID
Protein Name
3-hydroxy-3-methylglutaryl coenzyme A reductase
Ligand Name
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
XJLXINKUBYWONI-NNYOXOHSSA-N
SMILES
c1cc(c[n+](c1)C2C(C(C(O2)COP(=O)([O-])OP(=O)(O)OCC3C(C(C(O3)n4cnc5c4ncnc5N)OP(=O)(O)O)O)O)O)C(=O)N
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 6HR8
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Color Legend
Unassigned regionsLigand / hetero atomse6hr8A1e6hr8A2e6hr8B1e6hr8B2e6hr8C1e6hr8C2e6hr8D1e6hr8D2e6hr8E1e6hr8E2e6hr8F1e6hr8F2
ECOD domains from experimental PDB structures interacting with ligand DB03461
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| A0A4V8GZY0 | DB03461 | NAP | 6hr8 | e6hr8A1 | A:5-128,A:249-401 |
| A0A4V8GZY0 | DB03461 | NAP | 6hr8 | e6hr8A2 | A:129-248 |
| A0A4V8GZY0 | DB03461 | NAP | 6hr8 | e6hr8B1 | B:129-248 |
| A0A4V8GZY0 | DB03461 | NAP | 6hr8 | e6hr8B2 | B:5-128,B:249-400 |
| A0A4V8GZY0 | DB03461 | NAP | 6hr8 | e6hr8C1 | C:121-240 |
| A0A4V8GZY0 | DB03461 | NAP | 6hr8 | e6hr8C2 | C:6-120,C:241-401 |
| A0A4V8GZY0 | DB03461 | NAP | 6hr8 | e6hr8D1 | D:121-240 |
| A0A4V8GZY0 | DB03461 | NAP | 6hr8 | e6hr8D2 | D:6-120,D:241-401 |
| A0A4V8GZY0 | DB03461 | NAP | 6hr8 | e6hr8E1 | E:6-120,E:241-401 |
| A0A4V8GZY0 | DB03461 | NAP | 6hr8 | e6hr8E2 | E:121-240 |
| A0A4V8GZY0 | DB03461 | NAP | 6hr8 | e6hr8F1 | F:121-240 |
| A0A4V8GZY0 | DB03461 | NAP | 6hr8 | e6hr8F2 | F:6-120,F:241-401 |