Attributes
UniProt ID
Protein Name
proline--tRNA ligase
Ligand Name
4-[(3S)-3-cyano-3-(1-methylcyclopropyl)-2-oxidanylidene-pyrrolidin-1-yl]-N-[[3-fluoranyl-5-(1-methylpyrazol-4-yl)phenyl]methyl]-6-methyl-pyridine-2-carboxamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
PFICVJYRZDMEIX-MHZLTWQESA-N
SMILES
Cc1cc(cc(n1)C(=O)NCc2cc(cc(c2)F)c3cnn(c3)C)N4CCC(C4=O)(C#N)C5(CC5)C
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
Interactive Mol* view for the current protein-molecule pair.
Structure: 7F9S
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Color Legend
Unassigned regionsLigand / hetero atomse7f9sA1e7f9sA2e7f9sA3
ECOD domains from experimental PDB structures interacting with ligand 1TI
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| A0A7J6JUK2 | n/a | 1TI | 7f9s | e7f9sA2 | A:335-599 |
| A0A7J6JUK2 | n/a | 1TI | 7f9s | e7f9sA3 | A:720-830 |
| A0A7J6JUK2 | n/a | 1TI | 7f9u | e7f9uA2 | A:333-599 |
| A0A7J6JUK2 | n/a | 1TI | 7f9u | e7f9uB2 | B:332-599 |
| A0A7J6JUK2 | n/a | 1TI | 7f9u | e7f9uB3 | B:720-830 |
| A0A7J6JUK2 | n/a | 1TI | 7f9u | e7f9uC1 | C:332-599 |
| A0A7J6JUK2 | n/a | 1TI | 7f9u | e7f9uD3 | D:333-599 |
| A0A7J6JUK2 | n/a | 1TI | 7f9v | e7f9vA1 | A:720-830 |
| A0A7J6JUK2 | n/a | 1TI | 7f9v | e7f9vA3 | A:335-599 |
| A0A7J6JUK2 | n/a | 1TI | 7f9v | e7f9vB1 | B:335-599 |
| A0A7J6JUK2 | n/a | 1TI | 7f9v | e7f9vB2 | B:720-830 |
| A0A7J6JUK2 | n/a | 1TI | 7fan | e7fanA1 | A:331-599 |
| A0A7J6JUK2 | n/a | 1TI | 7fan | e7fanA3 | A:720-830 |
| A0A7J6JUK2 | n/a | 1TI | 7vc5 | e7vc5A2 | A:332-599 |
| A0A7J6JUK2 | n/a | 1TI | 7vc5 | e7vc5A3 | A:720-830 |