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Attributes

UniProt ID
A0PQG8
Protein Name
Dihydrofolate reductase
Ligand Name
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
DrugBank ID
DB03461
PDB Ligand Accession
NAP
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
XJLXINKUBYWONI-NNYOXOHSSA-N
SMILES
c1cc(c[n+](c1)C2C(C(C(O2)COP(=O)([O-])OP(=O)(O)OCC3C(C(C(O3)n4cnc5c4ncnc5N)OP(=O)(O)O)O)O)O)C(=O)N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Mol*
Structure: 6UWQ
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Color Legend
Unassigned regionsLigand / hetero atomse6uwqA1
ECOD domains from experimental PDB structures interacting with ligand DB03461
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
A0PQG8DB03461NAP6uwqe6uwqA1A:11-173
A0PQG8DB03461NAP6uwwe6uwwA1A:11-173
A0PQG8DB03461NAP7k68e7k68A1A:3-165
A0PQG8DB03461NAP7k69e7k69A1A:3-165
A0PQG8DB03461NAP7k6ae7k6aA1A:3-165
A0PQG8DB03461NAP7ki8e7ki8A1A:3-165
A0PQG8DB03461NAP7ki9e7ki9A1A:-4-165
A0PQG8DB03461NAP7km7e7km7A1A:3-165
A0PQG8DB03461NAP7km8e7km8A1A:2-165
A0PQG8DB03461NAP7km8e7km8B1B:2-165
A0PQG8DB03461NAP7km9e7km9A1A:3-165