DrugDomain logoDrugDomain

(2S)-2-[(3-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)methyl]-3,3-difluoropropanoic acid

A0PQG8 Dihydrofolate reductase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand WPD

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand WPD

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
A0PQG8n/a7km7WPDA202e7km7A1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
A0PQG8n/a7km8WPDA202e7km8A1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
A0PQG8n/a7km8WPDA202e7km8B1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
A0PQG8n/a7km8WPDB203e7km8A1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
A0PQG8n/a7km8WPDB203e7km8B1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1