DrugDomain logoDrugDomain

6-ethyl-5-[(3~{S})-3-(6-pyridin-4-yl-1,3-benzodioxol-4-yl)but-1-ynyl]pyrimidine-2,4-diamine

A4GRC7 — dihydrofolate reductase

← Back

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 5N1

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 5N1

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
A4GRC7n/a5ecx5N1A202e5ecxA1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
A4GRC7n/a5ecx5N1B202e5ecxB1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1