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6-ethyl-5-{3-[2-methoxy-5-(pyridin-4-yl)phenyl]prop-1-yn-1-yl}pyrimidine-2,4-diamine

A4GRC7 — dihydrofolate reductase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 6DR

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 6DR

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
A4GRC7n/a5ecc6DRA203e5eccA1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
A4GRC7n/a5ecc6DRB203e5eccB1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1