DrugDomain

Attributes

UniProt ID

A4TVL0

Protein Name

Cereblon isoform 4

Ligand Name

S-Thalidomide

DrugBank ID

None

PDB Ligand Accession

EF2

ChEMBL ID

n/a

PubChem ID

n/a

InChIKey

UEJJHQNACJXSKW-VIFPVBQESA-N

SMILES

c1ccc2c(c1)C(=O)N(C2=O)C3CCC(=O)NC3=O

Drug Action

No data available

Affinity Metrics

No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Mol*

Structure: 4V2Y

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Color Legend

Unassigned regionsLigand / hetero atomse4v2yA1e4v2yB1e4v2yC1

ECOD domains from experimental PDB structures interacting with ligand EF2

UniProt	DrugBank	PDB Ligand	PDB ID	ECOD Domain	Range Definition
A4TVL0	n/a	EF2	4v2y	e4v2yA1	A:19-123
A4TVL0	n/a	EF2	4v2y	e4v2yB1	B:20-123
A4TVL0	n/a	EF2	4v2y	e4v2yC1	C:18-123
A4TVL0	n/a	EF2	4v32	e4v32A1	A:19-123
A4TVL0	n/a	EF2	4v32	e4v32B1	B:20-123
A4TVL0	n/a	EF2	4v32	e4v32C1	C:18-123
A4TVL0	n/a	EF2	5amh	e5amhA1	A:18-123
A4TVL0	n/a	EF2	5ami	e5amiA1	A:20-123
A4TVL0	n/a	EF2	5ami	e5amiB1	B:20-123
A4TVL0	n/a	EF2	5amj	e5amjA1	A:18-124
A4TVL0	n/a	EF2	5amj	e5amjB1	B:19-123
A4TVL0	n/a	EF2	5amk	e5amkA1	A:19-123
A4TVL0	n/a	EF2	5amk	e5amkB1	B:19-123
A4TVL0	n/a	EF2	5amk	e5amkD1	D:14-124
A4TVL0	n/a	EF2	5oh1	e5oh1A1	A:19-123
A4TVL0	n/a	EF2	5oh1	e5oh1B1	B:20-123
A4TVL0	n/a	EF2	6r0s	e6r0sA1	A:16-124
A4TVL0	n/a	EF2	6r0s	e6r0sC1	C:17-123
A4TVL0	n/a	EF2	6r0u	e6r0uA1	A:16-124
A4TVL0	n/a	EF2	6r12	e6r12A1	A:16-124
A4TVL0	n/a	EF2	6r12	e6r12C1	C:18-124
A4TVL0	n/a	EF2	6r13	e6r13A1	A:16-123
A4TVL0	n/a	EF2	6r18	e6r18A1	A:14-124
A4TVL0	n/a	EF2	6r18	e6r18C1	C:18-123
A4TVL0	n/a	EF2	6r19	e6r19A1	A:13-123
A4TVL0	n/a	EF2	6r19	e6r19C1	C:16-124
A4TVL0	n/a	EF2	6r1a	e6r1aA1	A:13-124
A4TVL0	n/a	EF2	6r1a	e6r1aB1	B:13-123
A4TVL0	n/a	EF2	6r1a	e6r1aC1	C:16-123
A4TVL0	n/a	EF2	6r1c	e6r1cA1	A:14-123
A4TVL0	n/a	EF2	6r1c	e6r1cC1	C:18-124
A4TVL0	n/a	EF2	6r1w	e6r1wA1	A:13-124
A4TVL0	n/a	EF2	6r1w	e6r1wC1	C:18-123
A4TVL0	n/a	EF2	7pso	e7psoA1	A:16-123
A4TVL0	n/a	EF2	7pso	e7psoB1	B:20-123
A4TVL0	n/a	EF2	8bc7	e8bc7A1	A:16-123
A4TVL0	n/a	EF2	8bc7	e8bc7C1	C:18-123
A4TVL0	n/a	EF2	8ou3	e8ou3A1	A:16-123
A4TVL0	n/a	EF2	8ou3	e8ou3C1	C:18-123