DrugDomain

Attributes

UniProt ID

Protein Name

Ribonuclease L

Ligand Name

[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-3-hydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-3-hydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate

DrugBank ID

None

PDB Ligand Accession

25L

ChEMBL ID

n/a

PubChem ID

n/a

InChIKey

RTAGLZBJCCVJET-UQTMIEBXSA-N

SMILES

c1nc(c2c(n1)n(cn2)C3C(C(C(O3)COP(=O)(O)OC4C(C(OC4n5cnc6c5ncnc6N)COP(=O)(O)OC7C(C(OC7n8cnc9c8ncnc9N)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)O)O)N

Drug Action

No data available

Affinity Metrics

No affinity data available

3D Structure

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Mol*

Structure: 4O1O

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Color Legend

Unassigned regionsLigand / hetero atomse4o1oA1e4o1oA2e4o1oA3e4o1oB1e4o1oB2e4o1oB3e4o1oC1e4o1oC2e4o1oC3e4o1oD1e4o1oD2e4o1oD3

ECOD domains from experimental PDB structures interacting with ligand 25L

UniProt	DrugBank	PDB Ligand	PDB ID	ECOD Domain	Range Definition
A5H025	n/a	25L	4o1o	e4o1oA2	A:323-569
A5H025	n/a	25L	4o1o	e4o1oA3	A:22-322
A5H025	n/a	25L	4o1o	e4o1oB2	B:323-569
A5H025	n/a	25L	4o1o	e4o1oB3	B:22-322
A5H025	n/a	25L	4o1o	e4o1oC2	C:323-569
A5H025	n/a	25L	4o1o	e4o1oC3	C:22-322
A5H025	n/a	25L	4o1o	e4o1oD2	D:323-569
A5H025	n/a	25L	4o1o	e4o1oD3	D:22-322
A5H025	n/a	25L	4o1p	e4o1pA2	A:323-569
A5H025	n/a	25L	4o1p	e4o1pA3	A:22-322
A5H025	n/a	25L	4o1p	e4o1pB2	B:323-569
A5H025	n/a	25L	4o1p	e4o1pB3	B:22-322
A5H025	n/a	25L	4o1p	e4o1pC1	C:22-322
A5H025	n/a	25L	4o1p	e4o1pC2	C:333-583
A5H025	n/a	25L	4o1p	e4o1pD2	D:323-569
A5H025	n/a	25L	4o1p	e4o1pD3	D:22-322
A5H025	n/a	25L	6m12	e6m12a1	a:323-569
A5H025	n/a	25L	6m12	e6m12a2	a:22-322
A5H025	n/a	25L	6m12	e6m12b2	b:323-569
A5H025	n/a	25L	6m12	e6m12b3	b:24-322
A5H025	n/a	25L	6m13	e6m13a2	a:22-322
A5H025	n/a	25L	6m13	e6m13a3	a:323-569
A5H025	n/a	25L	6m13	e6m13b1	b:23-322
A5H025	n/a	25L	6m13	e6m13b2	b:323-569
A5H025	n/a	25L	7elw	e7elwa1	a:22-338
A5H025	n/a	25L	7elw	e7elwa2	a:333-584
A5H025	n/a	25L	7elw	e7elwb1	b:23-339
A5H025	n/a	25L	7elw	e7elwb2	b:333-584