(12S,15S)-N-[(2-fluorophenyl)methyl]-10,13-dioxo-12-{2-oxo-2-[(2R)-2-phenylpyrrolidin-1-yl]ethyl}-2-oxa-11,14-diazatricyclo[15.2.2.1~3,7~]docosa-1(19),3(22),4,6,17,20-hexaene-15-carboxamide

A5U4D6 — Proteasome subunit beta

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand U5Y

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand U5Y

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
A5U4D6	n/a	6wnk	U5Y	H	301	e6wnkH1	Ntn/PP2C	Ntn	Proteasome subunits	Proteasome
A5U4D6	n/a	6wnk	U5Y	H	301	e6wnkI1	Ntn/PP2C	Ntn	Proteasome subunits	Proteasome
A5U4D6	n/a	6wnk	U5Y	I	301	e6wnkI1	Ntn/PP2C	Ntn	Proteasome subunits	Proteasome
A5U4D6	n/a	6wnk	U5Y	I	301	e6wnkJ1	Ntn/PP2C	Ntn	Proteasome subunits	Proteasome
A5U4D6	n/a	6wnk	U5Y	J	301	e6wnkJ1	Ntn/PP2C	Ntn	Proteasome subunits	Proteasome
A5U4D6	n/a	6wnk	U5Y	J	301	e6wnkK1	Ntn/PP2C	Ntn	Proteasome subunits	Proteasome
A5U4D6	n/a	6wnk	U5Y	K	301	e6wnkK1	Ntn/PP2C	Ntn	Proteasome subunits	Proteasome
A5U4D6	n/a	6wnk	U5Y	K	301	e6wnkL1	Ntn/PP2C	Ntn	Proteasome subunits	Proteasome
A5U4D6	n/a	6wnk	U5Y	L	301	e6wnkL1	Ntn/PP2C	Ntn	Proteasome subunits	Proteasome
A5U4D6	n/a	6wnk	U5Y	L	301	e6wnkM1	Ntn/PP2C	Ntn	Proteasome subunits	Proteasome
A5U4D6	n/a	6wnk	U5Y	M	301	e6wnkM1	Ntn/PP2C	Ntn	Proteasome subunits	Proteasome
A5U4D6	n/a	6wnk	U5Y	M	301	e6wnkN1	Ntn/PP2C	Ntn	Proteasome subunits	Proteasome
A5U4D6	n/a	6wnk	U5Y	N	301	e6wnkH1	Ntn/PP2C	Ntn	Proteasome subunits	Proteasome
A5U4D6	n/a	6wnk	U5Y	N	301	e6wnkN1	Ntn/PP2C	Ntn	Proteasome subunits	Proteasome
A5U4D6	n/a	6wnk	U5Y	V	301	e6wnkV1	Ntn/PP2C	Ntn	Proteasome subunits	Proteasome
A5U4D6	n/a	6wnk	U5Y	V	301	e6wnkW1	Ntn/PP2C	Ntn	Proteasome subunits	Proteasome
A5U4D6	n/a	6wnk	U5Y	W	302	e6wnkW1	Ntn/PP2C	Ntn	Proteasome subunits	Proteasome
A5U4D6	n/a	6wnk	U5Y	W	302	e6wnkX1	Ntn/PP2C	Ntn	Proteasome subunits	Proteasome
A5U4D6	n/a	6wnk	U5Y	X	302	e6wnkX1	Ntn/PP2C	Ntn	Proteasome subunits	Proteasome
A5U4D6	n/a	6wnk	U5Y	X	302	e6wnkY1	Ntn/PP2C	Ntn	Proteasome subunits	Proteasome
A5U4D6	n/a	6wnk	U5Y	Y	301	e6wnkY1	Ntn/PP2C	Ntn	Proteasome subunits	Proteasome
A5U4D6	n/a	6wnk	U5Y	Y	301	e6wnkZ1	Ntn/PP2C	Ntn	Proteasome subunits	Proteasome
A5U4D6	n/a	6wnk	U5Y	Z	301	e6wnkZ1	Ntn/PP2C	Ntn	Proteasome subunits	Proteasome
A5U4D6	n/a	6wnk	U5Y	Z	301	e6wnka1	Ntn/PP2C	Ntn	Proteasome subunits	Proteasome
A5U4D6	n/a	6wnk	U5Y	a	301	e6wnka1	Ntn/PP2C	Ntn	Proteasome subunits	Proteasome
A5U4D6	n/a	6wnk	U5Y	a	301	e6wnkb1	Ntn/PP2C	Ntn	Proteasome subunits	Proteasome
A5U4D6	n/a	6wnk	U5Y	b	301	e6wnkV1	Ntn/PP2C	Ntn	Proteasome subunits	Proteasome
A5U4D6	n/a	6wnk	U5Y	b	301	e6wnkb1	Ntn/PP2C	Ntn	Proteasome subunits	Proteasome