DrugDomain logoDrugDomain

2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID

A7ASX7 Bifunctional dihydrofolate reductase-thymidylate synthase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB00642

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DB00642

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
A7ASX7DB006423k2hLYAA514e3k2hA2Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
A7ASX7DB006423k2hLYAB514e3k2hB2Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1