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Attributes

UniProt ID
Protein Name
Bifunctional dihydrofolate reductase-thymidylate synthase
Ligand Name
5-chloro-N~6~-(2,5-dimethoxybenzyl)quinazoline-2,4,6-triamine
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
ZQYDKYDSKVGDJP-UHFFFAOYSA-N
SMILES
COc1ccc(c(c1)CNc2ccc3c(c2Cl)c(nc(n3)N)N)OC
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 3JSU
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Color Legend
Unassigned regionsLigand / hetero atomse3jsuA2e3jsuA3e3jsuB2e3jsuB3
ECOD domains from experimental PDB structures interacting with ligand KA5
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
A7UD79n/aKA53jsue3jsuA2A:1-231
A7UD79n/aKA53jsue3jsuB2B:2-231