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5-(3-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)-6-ethylpyrimidine-2,4-diamine

A7UD81 — Bifunctional dihydrofolate reductase-thymidylate synthase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 9QO

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 9QO

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
A7UD81n/a6a2k9QOA701e6a2kA1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
A7UD81n/a6a2k9QOB701e6a2kB1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1