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5-(4-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)-6-ethylpyrimidine-2,4-diamine

A7UD81 — Bifunctional dihydrofolate reductase-thymidylate synthase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 9QR

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 9QR

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
A7UD81n/a6a2m9QRA701e6a2mA2Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
A7UD81n/a6a2m9QRB701e6a2mB1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1