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5,5'-[propane-1,3-diylbis(oxy-4,1-phenylene)]bis(6-ethylpyrimidine-2,4-diamine)

A7UD81 — Bifunctional dihydrofolate reductase-thymidylate synthase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 9RR

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 9RR

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
A7UD81n/a6a2o9RRA701e6a2oA1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
A7UD81n/a6a2o9RRB701e6a2oB2Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1