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spiro[1H-2-benzofuran-3,4'-piperidine]

A7UD81 — Bifunctional dihydrofolate reductase-thymidylate synthase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand GF3

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand GF3

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
A7UD81n/a7ctyGF3A702e7ctyA1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
A7UD81n/a7ctyGF3B902e7ctyB2Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1