N-cyclopropyl-6-[(3R)-3-{[4-(trifluoromethoxy)benzyl]carbamoyl}-4-{[4-(trifluoromethoxy)phenyl]sulfonyl}piperazin-1-yl]pyridazine-3-carboxamide
B1PBP5 — RNA-directed RNA polymerase
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand 63F
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand 63F
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| B1PBP5 | n/a | 3qgh | 63F | A | 601 | e3qghA1 | helical bundle domain in reverse transcriptase-like polymerases | helical bundle domain in reverse transcriptase-like polymerases | helical bundle domain in reverse transcriptase-like polymerases | RdRP_3 |
| B1PBP5 | n/a | 3qgh | 63F | A | 601 | e3qghA2 | Alpha-beta plaits | Adenylyl and guanylyl cyclase catalytic domain-like | Adenylyl and guanylyl cyclase catalytic domain-like | RdRP_3 |