(1aR,5S,8S,10R,22aR)-5-tert-butyl-N-{(1R,2S)-1-[(cyclopropylsulfonyl)carbamoyl]-2-ethenylcyclopropyl}-14-methoxy-3,6-di oxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadec ino[11,12-b]quinoxaline-8-carboxamide
C1KIK8 — NS3 protease
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand DB11575
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand DB11575
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| C1KIK8 | DB11575 | 6c2m | SUE | A | 1202 | e6c2mA1 | cradle loop barrel | RIFT-related | FMN-binding split barrel | Peptidase_S29 |
| C1KIK8 | DB11575 | 6c2m | SUE | B | 1202 | e6c2mB1 | cradle loop barrel | RIFT-related | FMN-binding split barrel | Peptidase_S29 |
| C1KIK8 | DB11575 | 6c2m | SUE | C | 1203 | e6c2mC1 | cradle loop barrel | RIFT-related | FMN-binding split barrel | Peptidase_S29 |
| C1KIK8 | DB11575 | 6c2m | SUE | D | 1202 | e6c2mD1 | cradle loop barrel | RIFT-related | FMN-binding split barrel | Peptidase_S29 |