DrugDomain logoDrugDomain

3'-[(2S)-4-(2,4-diamino-6-ethylpyrimidin-5-yl)but-3-yn-2-yl]-4'-methyl[1,1'-biphenyl]-4-carboxamide

C3TR70 — Dihydrofolate reductase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand ZM4

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand ZM4

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
C3TR70n/a7mqpZM4A201e7mqpA1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1