(2R)-4-(5-cyclopropyl[1,3]thiazolo[4,5-d]pyrimidin-2-yl)-N-[3-fluoro-4-(trifluoromethoxy)benzyl]-1-{[4-(trifluoromethyl)phenyl]sulfonyl}piperazine-2-carboxamide

D0PY27 — RNA-directed RNA polymerase

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB13095

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DB13095

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
D0PY27	DB13095	3vqs	JT1	A	1000	e3vqsA1	helical bundle domain in reverse transcriptase-like polymerases	helical bundle domain in reverse transcriptase-like polymerases	helical bundle domain in reverse transcriptase-like polymerases	RdRP_3
D0PY27	DB13095	3vqs	JT1	A	1000	e3vqsA2	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_3
D0PY27	DB13095	3vqs	JT1	B	601	e3vqsB3	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_3
D0PY27	DB13095	3vqs	JT1	B	601	e3vqsB4	helical bundle domain in reverse transcriptase-like polymerases	helical bundle domain in reverse transcriptase-like polymerases	helical bundle domain in reverse transcriptase-like polymerases	RdRP_3
D0PY27	DB13095	3vqs	JT1	C	601	e3vqsC3	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_3
D0PY27	DB13095	3vqs	JT1	C	601	e3vqsC4	helical bundle domain in reverse transcriptase-like polymerases	helical bundle domain in reverse transcriptase-like polymerases	helical bundle domain in reverse transcriptase-like polymerases	RdRP_3
D0PY27	DB13095	3vqs	JT1	D	1000	e3vqsD3	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	RdRP_3
D0PY27	DB13095	3vqs	JT1	D	1000	e3vqsD4	helical bundle domain in reverse transcriptase-like polymerases	helical bundle domain in reverse transcriptase-like polymerases	helical bundle domain in reverse transcriptase-like polymerases	RdRP_3