(1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid

D2WXL6 — ORF1a polyprotein

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand K36

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand K36

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
D2WXL6	n/a	7xjw	K36	A	401	e7xjwA1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
D2WXL6	n/a	7xjw	K36	A	401	e7xjwA2	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
D2WXL6	n/a	7xjw	K36	B	401	e7xjwB1	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
D2WXL6	n/a	7xjw	K36	B	401	e7xjwB2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
D2WXL6	n/a	7xjw	K36	C	401	e7xjwC1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
D2WXL6	n/a	7xjw	K36	C	401	e7xjwC2	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
D2WXL6	n/a	7xjw	K36	D	401	e7xjwD1	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
D2WXL6	n/a	7xjw	K36	D	401	e7xjwD2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
D2WXL6	n/a	7xjw	K36	E	401	e7xjwE1	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
D2WXL6	n/a	7xjw	K36	E	401	e7xjwE2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
D2WXL6	n/a	7xjw	K36	F	401	e7xjwE2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
D2WXL6	n/a	7xjw	K36	F	401	e7xjwF1	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
D2WXL6	n/a	7xjw	K36	F	401	e7xjwF2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
D2WXL6	n/a	7xjw	K36	G	401	e7xjwG1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
D2WXL6	n/a	7xjw	K36	G	401	e7xjwG2	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
D2WXL6	n/a	7xjw	K36	G	401	e7xjwH2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
D2WXL6	n/a	7xjw	K36	H	401	e7xjwG1	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
D2WXL6	n/a	7xjw	K36	H	401	e7xjwH1	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
D2WXL6	n/a	7xjw	K36	H	401	e7xjwH2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30