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4-[3-[3-[2,6-bis(azanyl)-5-(3-chlorophenyl)pyrimidin-4-yl]propoxy]phenoxy]butanoic acid

D9N170 — Bifunctional dihydrofolate reductase-thymidylate synthase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DQF

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DQF

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
D9N170n/a6kprDQFA703e6kprA2Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
D9N170n/a6kprDQFB703e6kprB2Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1