NICKEL (II) ION

E1K247 — Nickel-dependent hydrogenase large subunit

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand NI

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand NI

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
E1K247	n/a	4ucq	NI	Q	1551	e4ucqQ3	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ucq	NI	Q	1551	e4ucqQ4	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ucq	NI	R	1551	e4ucqR3	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ucq	NI	R	1551	e4ucqR4	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ucq	NI	S	1551	e4ucqS1	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ucq	NI	S	1551	e4ucqS2	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ucw	NI	Q	1551	e4ucwQ1	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ucw	NI	Q	1551	e4ucwQ3	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ucw	NI	R	1551	e4ucwR2	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ucw	NI	R	1551	e4ucwR3	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ucw	NI	S	1551	e4ucwS2	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ucw	NI	S	1551	e4ucwS3	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ud2	NI	Q	1551	e4ud2Q2	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ud2	NI	Q	1551	e4ud2Q4	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ud2	NI	R	1551	e4ud2R2	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ud2	NI	R	1551	e4ud2R3	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ud2	NI	S	1551	e4ud2S3	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ud2	NI	S	1551	e4ud2S4	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ud6	NI	Q	1551	e4ud6Q2	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ud6	NI	Q	1551	e4ud6Q3	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ud6	NI	R	1551	e4ud6R2	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ud6	NI	R	1551	e4ud6R4	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ud6	NI	S	1551	e4ud6S1	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ud6	NI	S	1551	e4ud6S3	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ue2	NI	Q	1551	e4ue2Q1	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ue2	NI	Q	1551	e4ue2Q4	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ue2	NI	R	1551	e4ue2R1	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ue2	NI	R	1551	e4ue2R2	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ue2	NI	S	1551	e4ue2S1	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ue2	NI	S	1551	e4ue2S3	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ue6	NI	Q	1551	e4ue6Q2	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ue6	NI	Q	1551	e4ue6Q3	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ue6	NI	R	1551	e4ue6R1	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ue6	NI	R	1551	e4ue6R4	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ue6	NI	S	1551	e4ue6S2	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ue6	NI	S	1551	e4ue6S3	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ueq	NI	Q	1551	e4ueqQ2	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
E1K247	n/a	4ueq	NI	Q	1551	e4ueqQ3	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ueq	NI	Q	1551	e4ueqQ4	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ueq	NI	R	1551	e4ueqR1	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ueq	NI	R	1551	e4ueqR2	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
E1K247	n/a	4ueq	NI	R	1551	e4ueqR4	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ueq	NI	S	1551	e4ueqS2	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
E1K247	n/a	4ueq	NI	S	1551	e4ueqS3	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ueq	NI	S	1551	e4ueqS4	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ueq	NI	T	1551	e4ueqT1	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ueq	NI	T	1551	e4ueqT2	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
E1K247	n/a	4ueq	NI	T	1551	e4ueqT3	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ueq	NI	U	1551	e4ueqU1	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
E1K247	n/a	4ueq	NI	U	1551	e4ueqU2	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ueq	NI	U	1551	e4ueqU4	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ueq	NI	V	1551	e4ueqV1	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ueq	NI	V	1551	e4ueqV3	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4ueq	NI	V	1551	e4ueqV4	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	alpha-helical domain in nickel-iron hydrogenase, large subunit	NiFeSe_Hases
E1K247	n/a	4upv	NI	Q	1551	e4upvQ3	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4upv	NI	Q	1551	e4upvQ4	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4upv	NI	R	1551	e4upvR2	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4upv	NI	R	1551	e4upvR3	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4uql	NI	Q	1551	e4uqlQ3	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4uql	NI	Q	1551	e4uqlQ4	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4uql	NI	R	1551	e4uqlR2	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4uql	NI	R	1551	e4uqlR3	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4urh	NI	Q	1551	e4urhQ1	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4urh	NI	Q	1551	e4urhQ3	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4urh	NI	R	1551	e4urhR1	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4urh	NI	R	1551	e4urhR3	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4urh	NI	S	1551	e4urhS1	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases
E1K247	n/a	4urh	NI	S	1551	e4urhS3	FAD-linked reductases, C-terminal domain-like	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	Ni-Fe binding domain in nickel-iron hydrogenase large subunit	NiFeSe_Hases