5-[2,5-bis(fluoranyl)phenyl]-3,4-dihydro-2~{H}-pyrrole

E2PUR9 — Beta-hydroxyacid dehydrogenase, 3-hydroxyisobutyrate dehydrogenase

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 4IS

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 4IS

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
E2PUR9	n/a	7y8l	4IS	A	302	e7y8lA1	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	NAD_binding_2
E2PUR9	n/a	7y8l	4IS	A	302	e7y8lA2	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	RedAm-like_C
E2PUR9	n/a	7y8l	4IS	A	302	e7y8lB1	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	RedAm-like_C
E2PUR9	n/a	7y8l	4IS	B	302	e7y8lA2	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	RedAm-like_C
E2PUR9	n/a	7y8l	4IS	B	302	e7y8lB1	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	RedAm-like_C
E2PUR9	n/a	7y8l	4IS	B	302	e7y8lB2	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	NAD_binding_2
E2PUR9	n/a	7y8l	4IS	C	303	e7y8lC1	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	RedAm-like_C
E2PUR9	n/a	7y8l	4IS	C	303	e7y8lD1	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	NAD_binding_2
E2PUR9	n/a	7y8l	4IS	C	303	e7y8lD2	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	RedAm-like_C
E2PUR9	n/a	7y8n	4IS	B	301	e7y8nA1	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	RedAm-like_C
E2PUR9	n/a	7y8n	4IS	B	301	e7y8nA2	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	NAD_binding_2
E2PUR9	n/a	7y8n	4IS	B	301	e7y8nB2	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	RedAm-like_C