(3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID

E8N6F3 — diphosphomevalonate decarboxylase

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DP6

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DP6

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
E8N6F3	n/a	6n0y	DP6	A	401	e6n0yA1	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	MVD-like_N
E8N6F3	n/a	6n0y	DP6	A	401	e6n0yA2	Alpha-beta plaits	GHMP Kinase, C-terminal domain	GHMP Kinase, C-terminal domain	MDD_C
E8N6F3	n/a	6n0y	DP6	B	401	e6n0yB1	Alpha-beta plaits	GHMP Kinase, C-terminal domain	GHMP Kinase, C-terminal domain	MDD_C
E8N6F3	n/a	6n0y	DP6	B	401	e6n0yB2	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	MVD-like_N
E8N6F3	n/a	6n0y	DP6	C	401	e6n0yC1	Alpha-beta plaits	GHMP Kinase, C-terminal domain	GHMP Kinase, C-terminal domain	MDD_C
E8N6F3	n/a	6n0y	DP6	C	401	e6n0yC2	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	MVD-like_N
E8N6F3	n/a	6n0y	DP6	D	401	e6n0yD1	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	MVD-like_N
E8N6F3	n/a	6n0y	DP6	D	401	e6n0yD2	Alpha-beta plaits	GHMP Kinase, C-terminal domain	GHMP Kinase, C-terminal domain	MDD_C
E8N6F3	n/a	6n0y	DP6	E	401	e6n0yE1	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	MVD-like_N
E8N6F3	n/a	6n0y	DP6	E	401	e6n0yE2	Alpha-beta plaits	GHMP Kinase, C-terminal domain	GHMP Kinase, C-terminal domain	MDD_C
E8N6F3	n/a	6n0y	DP6	F	401	e6n0yF1	Alpha-beta plaits	GHMP Kinase, C-terminal domain	GHMP Kinase, C-terminal domain	MDD_C
E8N6F3	n/a	6n0y	DP6	F	401	e6n0yF2	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	MVD-like_N
E8N6F3	n/a	6n0z	DP6	A	401	e6n0zA1	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	MVD-like_N
E8N6F3	n/a	6n0z	DP6	A	401	e6n0zA2	Alpha-beta plaits	GHMP Kinase, C-terminal domain	GHMP Kinase, C-terminal domain	MDD_C
E8N6F3	n/a	6n0z	DP6	B	401	e6n0zB1	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	MVD-like_N
E8N6F3	n/a	6n0z	DP6	B	401	e6n0zB2	Alpha-beta plaits	GHMP Kinase, C-terminal domain	GHMP Kinase, C-terminal domain	MDD_C
E8N6F3	n/a	6n0z	DP6	C	401	e6n0zC1	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	MVD-like_N
E8N6F3	n/a	6n0z	DP6	C	401	e6n0zC2	Alpha-beta plaits	GHMP Kinase, C-terminal domain	GHMP Kinase, C-terminal domain	MDD_C
E8N6F3	n/a	6n0z	DP6	D	401	e6n0zD1	Alpha-beta plaits	GHMP Kinase, C-terminal domain	GHMP Kinase, C-terminal domain	MDD_C
E8N6F3	n/a	6n0z	DP6	D	401	e6n0zD2	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	MVD-like_N
E8N6F3	n/a	6n0z	DP6	E	401	e6n0zE1	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	MVD-like_N
E8N6F3	n/a	6n0z	DP6	E	401	e6n0zE2	Alpha-beta plaits	GHMP Kinase, C-terminal domain	GHMP Kinase, C-terminal domain	MDD_C
E8N6F3	n/a	6n0z	DP6	F	401	e6n0zF1	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	MVD-like_N
E8N6F3	n/a	6n0z	DP6	F	401	e6n0zF2	Alpha-beta plaits	GHMP Kinase, C-terminal domain	GHMP Kinase, C-terminal domain	MDD_C