IRON/SULFUR CLUSTER

E9AE57 — Fumarate hydratase 2

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand SF4

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand SF4

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
E9AE57	n/a	5l2r	SF4	A	608	e5l2rA1	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	5l2r	SF4	A	608	e5l2rA2	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	5l2r	SF4	A	608	e5l2rA3	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	5l2r	SF4	B	611	e5l2rB1	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	5l2r	SF4	B	611	e5l2rB2	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	5l2r	SF4	B	611	e5l2rB3	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6msn	SF4	A	601	e6msnA1	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6msn	SF4	A	601	e6msnA2	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6msn	SF4	A	601	e6msnA3	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6msn	SF4	B	601	e6msnB1	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6msn	SF4	B	601	e6msnB2	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6msn	SF4	B	601	e6msnB3	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6unz	SF4	A	601	e6unzA1	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6unz	SF4	A	601	e6unzA2	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6unz	SF4	A	601	e6unzA3	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6unz	SF4	B	601	e6unzB1	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6unz	SF4	B	601	e6unzB2	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6unz	SF4	B	601	e6unzB3	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6unz	SF4	C	601	e6unzC1	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6unz	SF4	C	601	e6unzC2	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6unz	SF4	C	601	e6unzC3	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6unz	SF4	D	601	e6unzD1	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6unz	SF4	D	601	e6unzD2	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6unz	SF4	D	601	e6unzD3	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6unz	SF4	E	601	e6unzE1	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6unz	SF4	E	601	e6unzE2	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6unz	SF4	E	601	e6unzE3	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6unz	SF4	F	601	e6unzF1	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6unz	SF4	F	601	e6unzF2	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6unz	SF4	F	601	e6unzF3	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6unz	SF4	G	601	e6unzG1	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6unz	SF4	G	601	e6unzG2	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6unz	SF4	G	601	e6unzG3	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6unz	SF4	H	601	e6unzH1	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6unz	SF4	H	601	e6unzH2	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6unz	SF4	H	601	e6unzH3	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uo0	SF4	A	601	e6uo0A1	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uo0	SF4	A	601	e6uo0A2	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uo0	SF4	A	601	e6uo0A3	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6uo0	SF4	B	601	e6uo0B1	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6uo0	SF4	B	601	e6uo0B2	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uo0	SF4	B	601	e6uo0B3	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uoj	SF4	A	601	e6uojA1	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uoj	SF4	A	601	e6uojA2	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uoj	SF4	A	601	e6uojA3	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6uoj	SF4	B	601	e6uojB1	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uoj	SF4	B	601	e6uojB2	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uoj	SF4	B	601	e6uojB3	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6up9	SF4	A	604	e6up9A1	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6up9	SF4	A	604	e6up9A2	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6up9	SF4	A	604	e6up9A3	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6up9	SF4	B	604	e6up9B1	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6up9	SF4	B	604	e6up9B2	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6up9	SF4	B	604	e6up9B3	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6upm	SF4	A	601	e6upmA1	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6upm	SF4	A	601	e6upmA2	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6upm	SF4	A	601	e6upmA3	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6upm	SF4	B	601	e6upmB1	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6upm	SF4	B	601	e6upmB2	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6upm	SF4	B	601	e6upmB3	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6upo	SF4	A	601	e6upoA1	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6upo	SF4	A	601	e6upoA2	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6upo	SF4	A	601	e6upoA3	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6upo	SF4	B	601	e6upoB1	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6upo	SF4	B	601	e6upoB2	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6upo	SF4	B	601	e6upoB3	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6uq8	SF4	A	601	e6uq8A1	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uq8	SF4	A	601	e6uq8A2	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uq8	SF4	A	601	e6uq8A3	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6uq8	SF4	B	601	e6uq8B1	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6uq8	SF4	B	601	e6uq8B2	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uq8	SF4	B	601	e6uq8B3	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uq9	SF4	A	602	e6uq9A1	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uq9	SF4	A	602	e6uq9A2	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6uq9	SF4	A	602	e6uq9A3	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uq9	SF4	B	602	e6uq9B1	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6uq9	SF4	B	602	e6uq9B2	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uq9	SF4	B	602	e6uq9B3	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uqb	SF4	A	601	e6uqbA1	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uqb	SF4	A	601	e6uqbA2	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uqb	SF4	A	601	e6uqbA3	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6uqb	SF4	B	601	e6uqbB1	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uqb	SF4	B	601	e6uqbB2	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uqb	SF4	B	601	e6uqbB3	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6uql	SF4	A	601	e6uqlA1	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uql	SF4	A	601	e6uqlA2	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6uql	SF4	A	601	e6uqlA3	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uql	SF4	B	601	e6uqlB1	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6uql	SF4	B	601	e6uqlB2	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uql	SF4	B	601	e6uqlB3	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uqm	SF4	A	601	e6uqmA1	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6uqm	SF4	A	601	e6uqmA2	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uqm	SF4	A	601	e6uqmA3	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uqm	SF4	B	601	e6uqmB1	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uqm	SF4	B	601	e6uqmB2	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uqm	SF4	B	601	e6uqmB3	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6uqn	SF4	A	601	e6uqnA1	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6uqn	SF4	A	601	e6uqnA2	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uqn	SF4	A	601	e6uqnA3	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uqn	SF4	B	601	e6uqnB1	The "swivelling" beta/beta/alpha domains	FumA C-terminal domain-like	FumA C-terminal domain-like	Fumerase_C
E9AE57	n/a	6uqn	SF4	B	601	e6uqnB2	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase
E9AE57	n/a	6uqn	SF4	B	601	e6uqnB3	Thioredoxin-like	Fumarate hydratase N-terminal domain	Fumarate hydratase N-terminal domain	Fumerase