DrugDomain logoDrugDomain

N-[(6-methyl-2-oxo-4-propyl-1,2-dihydropyridin-3-yl)methyl]-6-[2-(4-methylpiperazin-1-yl)pyridin-4-yl]-1-(propan-2-yl)-1H-indazole-4-carboxamide

G0SDW4 — Histone-lysine N-methyltransferase EZH2

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand A97

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand A97

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
G0SDW4n/a5wfcA97B8009e5wfcB3beta-clipSET domain-likeSET domain-likeSET
G0SDW4n/a5wfcA97B8009e5wfcB5Ezh2 N-terminal domainEzh2 N-terminal domainEzh2 N-terminal domainEZH2_N