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5,8-dichloro-7-(3,5-dimethyl-1,2-oxazol-4-yl)-2-[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-3,4-dihydroisoquinolin-1(2H)-one

G1KPH4 — Histone-lysine N-methyltransferase EZH2

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand CJG

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand CJG

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
G1KPH4n/a6b3wCJGA708e6b3wA1beta-clipSET domain-likeSET domain-likeSET
G1KPH4n/a6b3wCJGA708e6b3wA5Ezh2 N-terminal domainEzh2 N-terminal domainEzh2 N-terminal domainEZH2_WD-Binding
G1KPH4n/a6b3wCJGB708e6b3wB5Ezh2 N-terminal domainEzh2 N-terminal domainEzh2 N-terminal domainEZH2_WD-Binding
G1KPH4n/a6b3wCJGB708e6b3wB6beta-clipSET domain-likeSET domain-likeSET