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1-{2-[4-(fluoroacetyl)piperazin-1-yl]ethyl}-4-methyl-5-[(4-{[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino}piperidin-1-yl)methyl]-1H-indole-2-carbonitrile

O00255 — Menin

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand EE7

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand EE7

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
O00255n/a6bxhEE7A603e6bxhA1Cysteine proteinases-likeCysteine proteinasesCysteine proteinasesMenin
O00255n/a6bxhEE7A603e6bxhA2Repetitive alpha hairpinsARM repeatARM repeatMenin