DrugDomain logoDrugDomain

4-methyl-1-{[(2S)-5-oxomorpholin-2-yl]methyl}-5-[(4-{[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino}piperidin-1-yl)methyl]-1H-indole-2-carbonitrile

O00255 — Menin

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand EEV

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand EEV

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
O00255n/a6bxyEEVA601e6bxyA1Repetitive alpha hairpinsARM repeatARM repeatMenin
O00255n/a6bxyEEVA601e6bxyA2Cysteine proteinases-likeCysteine proteinasesCysteine proteinasesMenin