DrugDomain logoDrugDomain

4-methyl-1-{[(2R)-5-oxomorpholin-2-yl]methyl}-5-[(4-{[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino}piperidin-1-yl)methyl]-1H-indole-2-carbonitrile

O00255 — Menin

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand FNV

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand FNV

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
O00255n/a6by8FNVA601e6by8A1Repetitive alpha hairpinsARM repeatARM repeatMenin
O00255n/a6by8FNVA601e6by8A2Cysteine proteinases-likeCysteine proteinasesCysteine proteinasesMenin