5-fluoro-2-({4-[7-({trans-4-[(methylsulfonyl)amino]cyclohexyl}methyl)-2,7-diazaspiro[3.5]nonan-2-yl]pyrimidin-5-yl}oxy)-N,N-di(propan-2-yl)benzamide
O00255 — Menin
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand OP4
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand OP4
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| O00255 | n/a | 6pkc | OP4 | A | 601 | e6pkcA1 | Cysteine proteinases-like | Cysteine proteinases | Cysteine proteinases | Menin |
| O00255 | n/a | 6pkc | OP4 | A | 601 | e6pkcA2 | Repetitive alpha hairpins | ARM repeat | ARM repeat | Menin |
| O00255 | n/a | 6pkc | OP4 | B | 601 | e6pkcB1 | Cysteine proteinases-like | Cysteine proteinases | Cysteine proteinases | Menin |
| O00255 | n/a | 6pkc | OP4 | B | 601 | e6pkcB2 | Repetitive alpha hairpins | ARM repeat | ARM repeat | Menin |