DrugDomain logoDrugDomain

methyl {(1S,2R)-2-[(1S)-2-(azetidin-1-yl)-1-(3-fluorophenyl)-1-{1-[(3-methoxy-1-{4-[(1S,4S)-5-propanoyl-2,5-diazabicyclo[2.2.1]heptane-2-sulfonyl]phenyl}azetidin-3-yl)methyl]piperidin-4-yl}ethyl]cyclopentyl}carbamate

O00255 — Menin

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand YQV

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand YQV

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
O00255n/a7m4tYQVA701e7m4tA1Repetitive alpha hairpinsARM repeatARM repeatMenin
O00255n/a7m4tYQVA701e7m4tA2Cysteine proteinases-likeCysteine proteinasesCysteine proteinasesMenin