DrugDomain logoDrugDomain

5-{(3R)-3-methyl-4-[(1R,2R)-2-methylcyclopropane-1-carbonyl]piperazin-1-yl}-3-(1-methyl-1H-pyrazol-4-yl)pyrazine-2-carbonitrile

O00329 — Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand M5D

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand M5D

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
O00329n/a6ocuM5DA1101e6ocuA5Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePI3_PI4_kinase