Attributes
UniProt ID
Protein Name
cGMP-dependent 3',5'-cyclic phosphodiesterase
Ligand Name
(3-bromo-4-fluorophenyl)[(5S)-3,3-difluoro-5-(5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)piperidin-1-yl]methanone
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
TTWAYHJJEHLVNR-LBPRGKRZSA-N
SMILES
Cc1cc(n2c(n1)ncn2)C3CC(CN(C3)C(=O)c4ccc(c(c4)Br)F)(F)F
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 5TZC
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Color Legend
Unassigned regionsLigand / hetero atomse5tzcA1e5tzcB1e5tzcC1e5tzcD1
ECOD domains from experimental PDB structures interacting with ligand 7OJ
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| O00408 | n/a | 7OJ | 5tzc | e5tzcA1 | A:576-918 |
| O00408 | n/a | 7OJ | 5tzc | e5tzcB1 | B:576-918 |
| O00408 | n/a | 7OJ | 5tzc | e5tzcC1 | C:578-917 |
| O00408 | n/a | 7OJ | 5tzc | e5tzcD1 | D:582-917 |
| O00408 | n/a | 7OJ | 5tzz | e5tzzA1 | A:576-917 |
| O00408 | n/a | 7OJ | 5tzz | e5tzzB1 | B:578-916 |
| O00408 | n/a | 7OJ | 5tzz | e5tzzC1 | C:590-916 |
| O00408 | n/a | 7OJ | 5tzz | e5tzzD1 | D:582-917 |