DrugDomain logoDrugDomain

3-(2,2,2-trifluoroethyl)-1-{(1S)-1-[4-(trifluoromethyl)phenyl]ethyl}-1H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

O00408 — cGMP-dependent 3',5'-cyclic phosphodiesterase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand FKV

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand FKV

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
O00408n/a6cybFKVA1008e6cybA1PDEase-likeHD-domain/PDEase-likeHD-domain/PDEase-likePDEase_I
O00408n/a6cybFKVB1006e6cybB1PDEase-likeHD-domain/PDEase-likeHD-domain/PDEase-likePDEase_I