[6-({5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}amino)-2,2-dimethyl-3-oxo-2,3-dihydro-4H-pyrido[3,2-b][1,4]oxazin-4-yl]methyl dihydrogen phosphate

O00444 — Serine/threonine-protein kinase PLK4

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB12010

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
O00444	DB12010	2RC	nD1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase, ABC1, Pkinase_fungal
O00444	DB12010	2RC	nD2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	Plk4_PB1

Show other predicted domains (99)

PDB ID	Domain Name	ECOD ID	X Group	H Group	T Group	F Group
2N19	e2n19A1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
3COK	e3cokB1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
3COK	e3cokA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
4JXF	e4jxfA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
4N7V	e4n7vA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e4n7vA2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e4n7vB1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e4n7vB2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4N7Z	e4n7zA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4N7Z	e4n7zA2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4N9J	e4n9jA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e4n9jA2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e4n9jB1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e4n9jB2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4YUR	e4yurA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
4YYP	e4yypA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
5LHY	e5lhyA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyB1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyC1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyD1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyE1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyF1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyG1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyH1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyI1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyJ1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyK1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyL1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyM1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyN1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyO1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyP1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyQ1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyR1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyS1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyT1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyU1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyV1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyW1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyX1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyY1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyZ1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhy11	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhy21	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhy31	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhy41	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhy51	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhy61	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhy71	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhy81	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhy91	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhya1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyb1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyc1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyd1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhye1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyf1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyg1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyh1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyi1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyj1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyk1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyl1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhym1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyn1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyo1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyp1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyq1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyr1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhys1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyt1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyu1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyv1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyw1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyx1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhyy1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
5LHZ	e5lhzA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhzB1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5lhzC1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
6N45	e6n45A1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e6n45A2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e6n45B1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e6n45B2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
6N46	e6n46A1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e6n46A2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e6n46B1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e6n46B2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e6n46C1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e6n46C2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e6n46D1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e6n46D2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e6n46E1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e6n46E2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e6n46F1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e6n46F2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e6n46G1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e6n46G2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e6n46H1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e6n46H2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box

ECOD domains from experimental PDB structures interacting with ligand DB12010

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
No experimental ECOD data found