Attributes
UniProt ID
Protein Name
Suppressor of cytokine signaling 2
Ligand Name
[4-[(2~{S})-3-[(4-fluoranyl-3-prop-2-enyl-phenyl)methylamino]-2-[2-(4-fluorophenyl)ethanoylamino]-3-oxidanylidene-propyl]phenyl] dihydrogen phosphate
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
YZWKPURPDOLTHG-VWLOTQADSA-N
SMILES
C=CCc1cc(ccc1F)CNC(=O)C(Cc2ccc(cc2)OP(=O)(O)O)NC(=O)Cc3ccc(cc3)F
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 7ZLR
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Color Legend
Unassigned regionsLigand / hetero atomse7zlrA1e7zlrA2e7zlrB1e7zlrC1
ECOD domains from experimental PDB structures interacting with ligand JH9
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| O14508 | n/a | JH9 | 7zlr | e7zlrA1 | A:145-198 |
| O14508 | n/a | JH9 | 7zlr | e7zlrA2 | A:30-144 |
| O14508 | n/a | JH9 | 7zls | e7zlsA1 | A:145-198 |
| O14508 | n/a | JH9 | 7zls | e7zlsA2 | A:30-144 |
| O14508 | n/a | JH9 | 7zls | e7zlsD1 | D:30-144 |
| O14508 | n/a | JH9 | 7zls | e7zlsD2 | D:145-198 |
| O14508 | n/a | JH9 | 7zls | e7zlsG1 | G:30-144 |
| O14508 | n/a | JH9 | 7zls | e7zlsG2 | G:145-198 |
| O14508 | n/a | JH9 | 7zls | e7zlsJ1 | J:145-198 |
| O14508 | n/a | JH9 | 7zls | e7zlsJ2 | J:30-144 |