~{N}-[(2~{S})-3-(3,4-dihydro-1~{H}-isoquinolin-2-yl)-2-oxidanyl-propyl]-3-pyridin-2-yl-benzamide
O14744 — Protein arginine N-methyltransferase 5
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand 5QH
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand 5QH
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| O14744 | n/a | 5emk | 5QH | A | 702 | e5emkA1 | Arginine methyltransferase oligomerization subdomain | Arginine methyltransferase oligomerization subdomain | Arginine methyltransferase oligomerization subdomain | PRMT5_C |
| O14744 | n/a | 5emk | 5QH | A | 702 | e5emkA2 | Rossmann-like | Rossmann-related | S-adenosyl-L-methionine-dependent methyltransferases | PRMT5 |