3-ethylimidazo[4,5-b]pyridin-2-amine
O14744 — Protein arginine N-methyltransferase 5
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand JYX
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand JYX
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| O14744 | n/a | 7zup | JYX | A | 702 | e7zupA2 | Rossmann-like | Rossmann-related | S-adenosyl-L-methionine-dependent methyltransferases | PRMT5 |
| O14744 | n/a | 7zup | JYX | A | 702 | e7zupA3 | Arginine methyltransferase oligomerization subdomain | Arginine methyltransferase oligomerization subdomain | Arginine methyltransferase oligomerization subdomain | PRMT5_C |