DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Aurora kinase A
Ligand Name
1-[3-methyl-4-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl}oxy)phenyl]-3-[3-(trifluoromethyl)phenyl]urea
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
INFGJUQNPPGDNS-UHFFFAOYSA-N
SMILES
Cc1cc(ccc1Oc2c(cccn2)c3ccnc(n3)NC)NC(=O)Nc4cccc(c4)C(F)(F)F
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 3EFW
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Color Legend
Unassigned regionsLigand / hetero atomse3efwA1e3efwB1
ECOD domains from experimental PDB structures interacting with ligand AK8
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
O14965n/aAK83efwe3efwA1A:126-388
O14965n/aAK83efwe3efwB1B:126-389