N-ACETYL-L-CYSTEINE

O15111 — Inhibitor of nuclear factor kappa-B kinase subunit alpha

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB06151

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
O15111	DB06151	SC2	nD1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase, Pkinase_fungal
O15111	DB06151	SC2	nD3	4177.2.1	BAR/IMD domain-like	Inhibitor of kappaB kinase beta dimerization domain	Inhibitor of kappaB kinase beta dimerization domain	IKBKB_SDD

Show other predicted domains (54)

PDB ID	Domain Name	ECOD ID	X Group	H Group	T Group	F Group
5EBZ	e5ebzA3	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e5ebzB2	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e5ebzC1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e5ebzD3	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e5ebzE2	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e5ebzF3	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e5ebzG2	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e5ebzH1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e5ebzI1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e5ebzJ2	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e5ebzK2	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e5ebzL2	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e5ebzA2	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
	e5ebzB1	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
	e5ebzC3	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
	e5ebzD1	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
	e5ebzE3	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
	e5ebzF1	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
	e5ebzG1	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
	e5ebzH3	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
	e5ebzI3	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
	e5ebzJ1	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
	e5ebzK3	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
	e5ebzL1	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
	e5ebzA1	4177.2.1	BAR/IMD domain-like	Inhibitor of kappaB kinase beta dimerization domain	Inhibitor of kappaB kinase beta dimerization domain	TBK1_CCD1
	e5ebzB3	4177.2.1	BAR/IMD domain-like	Inhibitor of kappaB kinase beta dimerization domain	Inhibitor of kappaB kinase beta dimerization domain	TBK1_CCD1
	e5ebzC2	4177.2.1	BAR/IMD domain-like	Inhibitor of kappaB kinase beta dimerization domain	Inhibitor of kappaB kinase beta dimerization domain	TBK1_CCD1
	e5ebzD2	4177.2.1	BAR/IMD domain-like	Inhibitor of kappaB kinase beta dimerization domain	Inhibitor of kappaB kinase beta dimerization domain	TBK1_CCD1
	e5ebzE1	4177.2.1	BAR/IMD domain-like	Inhibitor of kappaB kinase beta dimerization domain	Inhibitor of kappaB kinase beta dimerization domain	TBK1_CCD1
	e5ebzF2	4177.2.1	BAR/IMD domain-like	Inhibitor of kappaB kinase beta dimerization domain	Inhibitor of kappaB kinase beta dimerization domain	TBK1_CCD1
	e5ebzG3	4177.2.1	BAR/IMD domain-like	Inhibitor of kappaB kinase beta dimerization domain	Inhibitor of kappaB kinase beta dimerization domain	TBK1_CCD1
	e5ebzH2	4177.2.1	BAR/IMD domain-like	Inhibitor of kappaB kinase beta dimerization domain	Inhibitor of kappaB kinase beta dimerization domain	TBK1_CCD1
	e5ebzI2	4177.2.1	BAR/IMD domain-like	Inhibitor of kappaB kinase beta dimerization domain	Inhibitor of kappaB kinase beta dimerization domain	TBK1_CCD1
	e5ebzJ3	4177.2.1	BAR/IMD domain-like	Inhibitor of kappaB kinase beta dimerization domain	Inhibitor of kappaB kinase beta dimerization domain	TBK1_CCD1
	e5ebzK1	4177.2.1	BAR/IMD domain-like	Inhibitor of kappaB kinase beta dimerization domain	Inhibitor of kappaB kinase beta dimerization domain	TBK1_CCD1
	e5ebzL3	4177.2.1	BAR/IMD domain-like	Inhibitor of kappaB kinase beta dimerization domain	Inhibitor of kappaB kinase beta dimerization domain	TBK1_CCD1
5TQW	e5tqwA2	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e5tqwB2	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e5tqwA3	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
	e5tqwB3	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
	e5tqwA1	4177.2.1	BAR/IMD domain-like	Inhibitor of kappaB kinase beta dimerization domain	Inhibitor of kappaB kinase beta dimerization domain	TBK1_CCD1
	e5tqwB1	4177.2.1	BAR/IMD domain-like	Inhibitor of kappaB kinase beta dimerization domain	Inhibitor of kappaB kinase beta dimerization domain	TBK1_CCD1
5TQX	e5tqxA2	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e5tqxB2	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e5tqxA3	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
	e5tqxB3	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
	e5tqxA1	4177.2.1	BAR/IMD domain-like	Inhibitor of kappaB kinase beta dimerization domain	Inhibitor of kappaB kinase beta dimerization domain	TBK1_CCD1
	e5tqxB1	4177.2.1	BAR/IMD domain-like	Inhibitor of kappaB kinase beta dimerization domain	Inhibitor of kappaB kinase beta dimerization domain	TBK1_CCD1
5TQY	e5tqyA2	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e5tqyB2	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e5tqyA3	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
	e5tqyB3	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
	e5tqyA1	4177.2.1	BAR/IMD domain-like	Inhibitor of kappaB kinase beta dimerization domain	Inhibitor of kappaB kinase beta dimerization domain	TBK1_CCD1
	e5tqyB1	4177.2.1	BAR/IMD domain-like	Inhibitor of kappaB kinase beta dimerization domain	Inhibitor of kappaB kinase beta dimerization domain	TBK1_CCD1

ECOD domains from experimental PDB structures interacting with ligand DB06151

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
No experimental ECOD data found