METHOTREXATE
O15439 — ATP-binding cassette sub-family C member 4
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand DB00563
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand DB00563
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| O15439 | DB00563 | 8bwp | MTX | A | 1401 | e8bwpA2 | Type II ABC exporter transmembrane domain fold | Type I ABC exporter transmembrane domain fold | Type I ABC exporter transmembrane domain fold | ABC_membrane |
| O15439 | DB00563 | 8bwp | MTX | A | 1401 | e8bwpA3 | Type II ABC exporter transmembrane domain fold | Type I ABC exporter transmembrane domain fold | Type I ABC exporter transmembrane domain fold | ABC_membrane |